Alessandra GraziottinAlessandra Graziottin
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30/01/2012

Psychogenic causes of Chronic Pelvic Pain and impact of CPP on psychological status


Graziottin A.
Psychogenic causes of Chronic Pelvic Pain and impact of CPP on psychological status
in: Vercellini P. (Ed), Chronic pelvic pain, Blackwell Publishing, Oxford, UK, 2011, p. 29-39

Psychogenic factors can be powerful contributors of CPP, as predisposing, precipitating or maintaining factors of chronic stress. One of the currently most credited pathophysiologic reading is through the corticotropin-releasing factor (CRF) signaling pathways.
The paper updates the word ”psychogenic”; suggests a pathophysiologic reading of the psychogenic contribute to CPP, via the stress-induced corticotropin-releasing factor (CRF) signaling pathways, and differentiates predisposing, precipitating and maintaining factors; summarizes the pertinent evidence; focuses on the differential diagnosis between prominent “psychogenic” vs somatic etiology of CPP; highlights the common diagnostic mistakes with a focus on iatrogenic factors and nocebo effect; discusses the psychological and sexual consequences of CPP.

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